PureTech Health (LSE:PRTC, NASDAQ:PRTC, OTC:PTCHF) PLC announced a lucrative royalty deal with Royalty Pharma for its KarXT drug, developed by Karuna Therapeutics. In response, Liberum, the corporate broker, has increased its target price for PureTech Health from 420p to 470p, reiterating its 'buy' recommendation.

PureTech Health remains undervalued after KarXCT deal, says broker

Shares in PureTech Health (LSE:PRTC, NASDAQ:PRTC, OTC:PTCHF) PLC jumped 10% after it agreed a US$500mln royalty deal, US$100mln of which will be paid upfront. In the first half hour of trading the shares were up 21.49p at  224.49p.

PureTech Health shares jump 10% on US$500mln royalty deal

BOSTON--(BUSINESS WIRE)--PureTech Health plc (Nasdaq: PRTC, LSE: PRTC) ("PureTech" or the "Company"), a clinical-stage biotherapeutics company dedicated to changing the treatment paradigm for devastating diseases, today announced that Daphne Zohar, Founder and Chief Executive Officer, and Julie Krop, M.D.

PureTech to Present at the Jefferies London Healthcare Conference

BOSTON--(BUSINESS WIRE)--PureTech to Present at the Credit Suisse 31st Annual Healthcare Conference

PureTech to Present at the Credit Suisse 31st Annual Healthcare Conference

PureTech Health (LSE:PRTC, NASDAQ:PRTC, OTC:PTCHF) PLC and Nektar Therapeutics (NASDAQ:NKTR) said they have mutually agreed to terminate discussions regarding a possible combination of the two companies.  The talks were first announced on 7 October 2022 in response to press speculation.

PureTech Health and Nektar Therapeutics end tie-up talks

PureTech Health (LSE:PRTC, NASDAQ:PRTC, OTC:PTCHF) PLC has confirmed that it is in talks about a possible tie-up with Nektar Therapeutics (NASDAQ:NKTR), Inc.  Responding to press speculation, PureTech said it has exchanged indicative, non-binding proposals with Nektar Therapeutics regarding a possible combination, which may include an offer for the share capital of PureTech.  “PureTech and Nektar remain in discussions regarding the proposal.

PureTech Health confirms ‘possible combination' with Nektar Therapeutics

PureTech Health plc, a clinical-stage biotherapeutics company, discovers, develops, and commercializes medicines for inflammatory, fibrotic and immunological, intractable cancers, lymphatic and gastrointestinal, neurological and neuropsychological, and other diseases in the United States. The company offers KarXT targeting muscarinic acetylcholine receptors to treat schizophrenia and psychosis in Alzheimer's disease; a regenerative biology platform for androgenetic alopecia, epithelial ageing, and other medical conditions; an immunomodulation platform to treat chronic and acute inflammatory disorders; oral therapies based on defined consortia of bacteria is isolated from the human microbiome; and therapies to treat cognitive dysfunction associated with depression, multiple sclerosis, post COVID and ICU, and cancer related conditions. It also provides hematopoietic stem cell based therapies for patients with blood cancer; a voice-based technology platform to detect voice changes linked to health conditions; and a technology platform for the oral delivery of biologics, vaccines, and other drugs. In addition, the company is developing LYT-100 to treat lymphedema, and other lymphatic flow disorders; LYT-200, a IgG4 monoclonal antibody to target galectin-9; LYT-210 to treat solid tumors; Glyph, a synthetic lymphatic targeting chemistry platform; Orasome technology to enable the oral administration of macromolecule therapeutic payloads; meningeal lymphatics platform to treat Alzheimer's and Parkinson's diseases; and Alivio technology platform for inflammation-targeted disease immunomodulation. PureTech Health plc has collaboration and license agreements with Boehringer Ingelheim International GMBH; Eli Lilly and Company; Imbrium Therapeutics L.P.; and Shionogi & Co., Ltd. The company was incorporated in 2015 and is headquartered in Boston, Massachusetts.